The U.S. Food and Drug Administration (FDA) issued a safety alert for soft tissue fillers. The information obtained by the FDA indicates that the unintentional injection of soft tissue filler into the blood vessels of the face can result in rare, but serious side effects. The soft tissue fillers, also called dermal fillers, injectable facial implants or wrinkle fillers, are used to create a smoother or fuller appearance of the face, to reduce the appearance of wrinkles or to augment the lips or cheeks.

The side effect is that the unintentional injection can block blood vessels and restrict the blood supply to tissues which sometimes results in embolization, where the filler material travels to other parts of the body. The embolization can cause blindness, stroke and damage and/or death to the skin (necrosis).

The FDA has identified certain sites that have a higher risk of blockage in its Safety Bulletin on its website. For further information and to report any adverse reactions, please see visit: